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Closed-Loop Sacral Neuromodulation

Exploring a new way to treat overactive bladder

Current Challenges of
Treating Refractory Overactive Bladder

Overactive bladder (OAB) is a common condition affecting millions of people in the world over the age of 40. OAB is characterized by urinary urgency, frequency, and incontinence, which can have a significant impact on quality of life.


Although there are several treatment options available for OAB, refractory cases continue to pose a challenge. Current implantable sacral neuromodulation is a promising approach for managing refractory OAB, but there are still several drawbacks to address. These include invasiveness, over stimulation complications, limited therapeutic efficacy, and the need for frequent surgeries.

Our  Solution

INOPASE offers a cutting-edge closed-loop stimulation technology for refractory OAB, with a vision of ultimately curing the disease. Our innovative solution offers several advantages, including:

  1. Pre-symptomatic detection: Timely stimulation to prevent symptoms before they occur, tailored to each patient for optimal treatment.

  2. Personalized treatment: Stimulation adaptable to individual condition, ensuring that each patient receives the most effective treatment possible.

  3. Minimally invasive: Miniaturized device enables same-day implant surgery, reducing the burden on patients and improving their quality of life.

  4. Complete remission - Symptom Free: Complete regeneration of neural function to achieve a symptom-free life.


Together, these features make our solution a highly promising and innovative approach to managing refractory OAB, with the potential to significantly improve patients' lives.

Collaboration  of  Technologies  and  Clinical  Knowledge

Fukushima Medical University

Fukushima Medical University

Dokkyo Medical University

Dokkyo Medical University

Wireless Powered Closed Loop Neuromodulation

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