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Closed-Loop Brain Neuromodulation

Exploring a new way of treating epilepsy

Current Challenges of
Treating Drug-Resistant Epilepsy

Drug-resistant epilepsy (DRE) is a condition in which patients do not respond to available medications and experience recurrent seizures. DRE affects a significant portion of the global population with at least 30% of epilepsy patients experiencing this condition. Unfortunately, available treatment options such as surgery or medication adjustments may not effectively manage DRE patients, and pose side effects or risks.

Although there is a promising solution for DRE known as neuromodulation, there are still several drawbacks that need to be addressed, including limited efficacy, imprecise stimulation, and non-personalized treatment.

Our  Solution

INOPASE offers a cutting-edge closed-loop stimulation technology for DRE, with a vision to improve current neuromodulation drawbacks. Our innovative solution offers several advantages, including:


  1. Pre-symptomatic detection: Timely stimulation to prevent symptoms before they occur, tailored to each patient for optimal treatment.

  2. Personalized treatment: Stimulation adaptable to individual condition, ensuring that each patient receives the most effective treatment possible.

  3. Broad, high-density EEG recordings: We offer 64-128 implantable electrodes with thinner and more flexible material, to identify the precise epileptic onset zone.

  4. Precise Stimulation: By using broad and high-density electrodes, doctors can locate the optimal brain site for precise stimulation, improving treatment outcomes.    

Together, these features make our solution a highly promising and innovative approach to managing DRE, with the potential to significantly improve patients' lives.

Collaboration  of  Technologies  and  Clinical  Knowledge


Yokohama City University 


Tokyo Institute of Technolog

Wireless Powered Closed Loop Neuromodulation

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